• Release of chitobiase as an indicator of potential molting disruption in juvenile Daphnia magna exposed to the ecdysone receptor agonist 20-hydroxyecdysone 

      Song, You; Evenseth, Linn Mari; Iguchi, Taisen; Tollefsen, Knut Erik (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-08-29)
      During arthropod molting, the old exoskeleton is degraded and recycled by the molting fluid. Chitobiase, a major chitinolytic enzyme in the molting fluid, has been widely used as a biomarker to indicate endocrine disruption of molting in arthropods under environmental stress. Although release of chitobiase was extensively studied in organisms exposed to molting-inhibiting chemicals, enzymic association ...
    • Structure, function and ligand interactions of the ecdysone receptor from Daphnia magna 

      Evenseth, Linn Mari (Master thesis; Mastergradsoppgave, 2014-06-02)
      Background: Endocrine disruptors are of an increasing concern to the global environment due to their ability to modulate endocrine processes and cause adverse apical effects. Invertebrates are important species in the aquatic environment and are a central subject for toxicological testing, but the effects of endocrine disruptors (EDs) in invertebrates are limited due to less knowledge concerning the ...
    • Whole-Organism Transcriptomic Analysis Provides Mechanistic Insight into the Acute Toxicity of Emamectin Benzoate in Daphnia magna 

      Song, You; Rundberget, Thomas; Evenseth, Linn Mari; Xie, Li; Gomes, Tania; Høgåsen, Tore; Iguchi, Taisen; Tollefsen, Knut Erik (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-10-05)
      Emamectin benzoate (EMB) is an antisea lice chemical widely used in the aquaculture that may also unintentionally affect nontarget crustaceans in the environment. Although the adverse effects of this compound are well documented in various species, the full modes of action (MoAs) are still not well characterized. The current study was therefore conducted to characterize the MoAs of EMB and link ...